GALNT12 suppresses the bone-specific prostate cancer metastasis by activating BMP pathway via the

O-glycosylation of BMPR1A

Yang Yang^1#, Meng Ding^1#, Haoli Yin^2#, Wei Chen¹, Hongwei Shen¹, Wenli Diao¹, Lin Yang¹, Haixiang Qin¹, Weidong Gan^1*, Xuefeng Qiu¹ and Hongqian Guo^1*

Small interfering RNA (siRNA) against human GALNT12 were purchased from Generay (Shanghai, China) and transfected into Lncap cells with INTERFERin@

(Polyplus, France).

The relative expression of mRNA was normalized to ACTB by the 2-ΔCtΔCt method and the primers purchased from Generay (Shanghai, China) were listed in Table S1.